Genomic Characterization of a Mangrove-Derived Endophytic Fungus from Avicennia officinalis

Endophytic fungi inhabiting mangrove ecosystems are recognized as rich sources of novel bioactive compounds and unique metabolic capabilities. In this study, we present the genomic characterization of an endophytic fungus isolated from the mangrove plant Avicennia officinalis. High-quality genomic DNA was sequenced and assembled to generate a comprehensive genome dataset, enabling detailed insights into its genetic makeup. Functional annotation revealed a diverse array of genes associated with secondary metabolite biosynthesis, stress tolerance, and plant–microbe interactions, highlighting the adaptive strategies of the fungus in the challenging mangrove environment. Additionally, gene clusters involved in polyketide and non-ribosomal peptide synthesis suggest significant potential for the production of pharmacologically important compounds. Comparative genomic analysis further indicated evolutionary relationships with related fungal taxa and emphasized unique genomic traits linked to its endophytic lifestyle. Overall, this study enhances our understanding of mangrove-associated endophytic fungi and underscores their potential as valuable resources for biotechnology and natural product discovery